education&mythtesting&technology

What Does 99% DNA Test Accuracy Really Mean for You?

In a world full of wellness fads and health advice, your DNA doesn’t lie. But what does it really mean when we, genetic testing company, say your DNA test is “99% accurate”? And how does that impact the way you use your results?

Let’s break it down.

✅ Reliable Data You Can Trust

At SuperDNA, your genetic sample is analysed using cutting-edge genotyping or sequencing technology, processed in ISO-certified laboratories, and interpreted using evidence-based scientific models. This allows us to read your genetic code with over 99% technical accuracy.

SNP genotyping platforms, like those used in clinical and research settings, demonstrate call rates of 99.5–99.9%, with over 99% concordance between duplicates【1】【2】.
Even low-coverage whole genome or exome sequencing methods typically achieve >99% accuracy when processed using validated pipelines【3】.

This means the presence or absence of a gene variant in your report is highly reliable — a critical foundation before any interpretation begins.


🏅 ISO-Certified Labs: Why It Matters

SuperDNA laboratory certified under ISO 15189 and ISO/IEC 17025, internationally recognised standards for:

  • Medical laboratory quality

  • Technical competence in testing and calibration

  • Reproducible, reliable results

These standards ensure that from sample handling to data reporting, the entire process follows strict quality control protocols【4】.


💼 Medical Device Approval (MDA): What It Means for You

SuperDNA’s sample collection kits are registered with Malaysia’s Medical Device Authority (MDA) under the Medical Device Act 2012 (Act 737). This confirms that:

  • The kits are safe, validated, and manufactured under Good Manufacturing Practice (GMP)

  • The materials are medically approved for human biological sample collection【5】

Together, these elements ensure that both sample collection and laboratory analysis meet global health and safety benchmarks.


📊 Confident, Personalised Recommendations

We don’t stop at accurate lab data. SuperDNA uses Polygenic Risk Score (PRS) models that aggregate the effects of hundreds to thousands of genetic variants — offering a far more comprehensive prediction of risk for common, complex diseases like:

  • Diabetes

  • Heart disease

  • Obesity

  • Breast cancer and many more

PRS is now recognised in academic and clinical settings as a statistically robust way to estimate an individual’s disease risk based on their genetic profile【6】【7】.

These scores are built using results from Genome-Wide Association Studies (GWAS), which have identified thousands of genetic markers associated with specific health traits. SuperDNA references both global and Asian-specific datasets to ensure cultural and population relevance【8】【9】.


🚫 But It’s Not a Crystal Ball

While the genetic data is accurate, it’s still not a diagnosis. DNA testing shows your genetic predisposition, not your destiny.

  • You may carry gene variants associated with high cholesterol, but your lifestyle choices still greatly influence whether you develop the condition.

  • You may be genetically sensitive to caffeine, but the impact on your energy or sleep can still vary based on your environment and habits.


❤️ Why It Matters

Think of your DNA report as your personal health GPS.
It doesn’t decide your destination — but it helps you start with a clearer, more accurate map of where you’re starting from.

When your DNA is tested with 99% accuracy, in ISO-certified labs, using MDA-approved kits, and interpreted through globally validated scientific models — you’re empowered to make smarter, more personalised health choices.


Ready to decode your DNA?
Explore our DNA health and wellness solutions at mysuperdna.com or message us to get started now!

References

  1. Illumina. (2020). Genotyping Microarray Performance Summary. https://www.illumina.com

  2. Gunderson, K. L. (2009). Whole-genome genotyping on bead arrays. Methods in Molecular Biology, 529, 197–213.

  3. Bentley, D. R., et al. (2008). Accurate whole human genome sequencing using reversible terminator chemistry. Nature, 456(7218), 53–59.

  4. ISO. (2022). ISO 15189:2022 – Medical laboratories — Requirements for quality and competence. https://www.iso.org

  5. Medical Device Authority Malaysia. (2023). Medical Device Act 2012 (Act 737). https://www.mda.gov.my

  6. Torkamani, A., Wineinger, N. E., & Topol, E. J. (2018). The personal and clinical utility of polygenic risk scores. Nature Reviews Genetics, 19(9), 581–590.

  7. Lewis, C. M., & Vassos, E. (2020). Polygenic risk scores: from research tools to clinical instruments. Genome Medicine, 12(1), 44.

  8. Lam, M., et al. (2019). Comparative genetic architectures of schizophrenia in East Asian and European populations. Nature Genetics, 51(12), 1670–1678.

  9. Teo, Y. Y. (2021). Population-specific reference panels and polygenic risk scores: are we ready for the clinic? Human Genetics, 140, 563–574.

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